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LOCUS AE005210 12144 bp DNA BCT 21-MAR-2001
DEFINITION Escherichia coli O157:H7 EDL933 genome, contig 1 of 3, section 34
of 155.
ACCESSION AE005210 AE005174
VERSION AE005210.1 GI:12513129
KEYWORDS .
SOURCE Escherichia coli O157:H7 EDL933.
ORGANISM Escherichia coli O157:H7 EDL933
Bacteria; Proteobacteria; gamma subdivision; Enterobacteriaceae;
Escherichia.
REFERENCE 1 (bases 1 to 12144)
AUTHORS Perna,N.T., Plunkett,G. III, Burland,V., Mau,B., Glasner,J.D.,
Rose,D.J., Mayhew,G.F., Evans,P.S., Gregor,J., Kirkpatrick,H.A.,
Posfai,G., Hackett,J., Klink,S., Boutin,A., Shao,Y., Miller,L.,
Grotbeck,E.J., Davis,N.W., Lim,A., Dimalanta,E., Potamousis,K.,
Apodaca,J., Anantharaman,T.S., Lin,J., Yen,G., Schwartz,D.C.,
Welch,R.A. and Blattner,F.R.
TITLE Genome sequence of enterohaemorrhagic Escherichia coli O157:H7
JOURNAL Nature 409 (6819), 529-533 (2001)
MEDLINE 21074935
PUBMED 11206551
REFERENCE 2 (bases 1 to 12144)
AUTHORS Perna,N.T., Plunkett,G. III, Burland,V., Mau,B., Glasner,J.D.,
Rose,D.J., Mayhew,G.F., Evans,P.S., Gregor,J., Kirkpatrick,H.A.,
Posfai,G., Hackett,J., Klink,S., Boutin,A., Shao,Y., Miller,L.,
Grotbeck,E.J., Davis,N.W., Lim,A., Dimalanta,E., Potamousis,K.,
Apodaca,J., Anantharaman,T.S., Lin,J., Yen,G., Schwartz,D.C.,
Welch,R.A. and Blattner,F.R.
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2000) Laboratory of Genetics, University of
Wisconsin, 445 Henry Mall, Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..12144
/organism="Escherichia coli O157:H7 EDL933"
/strain="EDL933"
/serotype="O157:H7"
/db_xref="taxon:155864"
/note="enterohemorrhagic"
misc_feature <1..4460
/note="O-island #15; Region of the EDL933 chromosome not
homologous to E. coli K-12 MG1655"
gene 285..4334
/gene="Z0402"
CDS 285..4334
/gene="Z0402"
/function="putative membrane; Extracellular functions:
Secreted proteins"
/note="Residues 874 to 1349 of 1349 are 55.13 pct
identical to residues 5 to 466 of 466 from GenPept 118 :
gi|1787787|gb|AAC74582.1| (AE000248) putative ATP-binding
component of a transport system and adhesin protein
[Escherichia coli]"
/codon_start=1
/transl_table=11
/product="putative beta-barrel outer membrane protein"
/protein_id="AAG54657.1"
/db_xref="GI:12513130"
/translation="MAFNALLFMQSWFYLDVLLEIVMNKIYRLKWNRSRNCWSVCSEL
GSRVKGKKSRAVLISAISLYSSLVFADDVIVNQDKTIDFGKENQSIDYRITVTDNANL
VINATDTSRPRLTLASGGGLDITGGKVTINGPLNFLLKGTGFLNVSNAGSELYADDLY
ESNSGMRHDRGYFNVSNGGKIHVKGTSRLTYLQGNVSGEGSQVNSETFFMGVYGSYGG
NQYLSVNNGGEVNARKQISLGYYDQVSDTTLAVSEGGKISAPTISLSTNSELALGAQE
GSAAKAAGIIDAEKIEFVWAKTSEKKITLNHTDKDATISADIVSGSEGLGYINALNGT
TYLTGDNSAFSGKVKIEQNGALGITQNIGTAEINNRGKLHLKADDSMTFANKISGNGT
ISIDSGTVELTGNNYAFSGYIDVASGAVAVISEDKNIGRAELDVDGKLQINANKDWVF
DNDLEGRGIVEINMGNHEFSFDEFAYTDWFQGSLAFQNTTFNLEKNAEFLQKGGITAG
QGSLVTVGKGAHSISTLGFSGGTVDFGALTAGAQMTEGTVNVSKTLDLRGEGVIQVSD
SDVVRSVSRDIDSALSLTEVDDGNSTIKLVDAQGAEVLGDAGNLQLQDKNGQILSSSA
QRDIQQNGQKAAVGTYDYRLTSGVNNDGLYIGYGLTQLDLHATDSDALVLSSNGKSEN
AADLSAKITGSGDLAFSSQKGQTVSLSNKDNDYTGVTDLRSGTLLLNNDNVLGNTHEL
RLAAETELDMNGHSQTVGTLNGSADSLLSLNGGSLTVTNGGTSTGSLTGSGELNIQGG
TLDIAGDNSNLTANVNIANSANVLVSHAQGLGSANVENNGTLALNNSAEKRAAASVNY
ALGGNLTNNGTLMTGMSGQQAGNVLVVKGNYHGNNGQLVMNTVLNGDDSVTDKLVVEG
DTSGTTAVTVNNAGGTGAKTLNGIELIHVDGKSEGEFVQAGRIVAGAYDYTLARGQGA
NSGNWYLTSGSDSPELQPEPDPMPNPEPNPNPEPNPNPTPTPGPDLNVDNDLRPEAGS
YIANLAAANTMFTTRLHERLGNTYYTDMVTGEQKQTTMWMRHEGGHNKWRDGSGQLKT
QSNRYVLQLGGDVAQWSQNGSDRWHVGVMAGYGNSDSKTISSRTGYRAKASVNGYSTG
LYATWYADDESRNGAYLDSWAQYSWFDNTVKGDDLQSESYKSKGFTASLEAGYKHKLA
EFNGSQGTRNEWYVQPQAQVTWMGVKADKHRESNGTLVHSNGDGNVQTRLGVKTWLKS
HHKMDDGKSREFQPFVEVNWLHNSKDFSTSMDGVSVTQDGARNIAEIKTGVEGQLNAN
LNVWGNVGVQVADRGYNDTSAMVGIKWQF"
gene 4467..5564
/gene="yahA"
/note="Z0403"
CDS 4467..5564
/gene="yahA"
/function="orf; Unknown function"
/note="Residues 4 to 365 of 365 are 93.09 pct identical to
residues 1 to 362 of 362 from Escherichia coli K-12 Strain
MG1655: B0315"
/codon_start=1
/transl_table=11
/product="orf, hypothetical protein"
/protein_id="AAG54658.1"
/db_xref="GI:12513131"
/translation="MCSMASHDLSVFLEEFGATVNLTLPGIVSEKERLLLKLLMEGMS
VTEISQYRNRSAKTISHQKKQLYEKLGIQSDITFWRDIFFQYHPQVISGTGNKNNFYI
PDNRCHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPD
QFIPLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKEC
LNLVKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRY
LQAFPVDFIKIDKSFVQMAGVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMI
GKGVHFLQGYLYSPPVPGNKFISEWVMKAGG"
gene complement(5606..5866)
/gene="Z0404"
CDS complement(5606..5866)
/gene="Z0404"
/function="orf; Unknown function"
/note="Residues 1 to 86 of 86 are 96.51 pct identical to
residues 225 to 310 of 310 from Escherichia coli K-12
Strain MG1655: B0316"
/codon_start=1
/transl_table=11
/protein_id="AAG54659.1"
/db_xref="GI:12513132"
/translation="MPDFNTKCQCQILGEGIVFLPDYMVREAMAQSLLVTRQIHNPRQ
DSRMLLATQHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
gene complement(5827..6537)
/gene="Z0405"
CDS complement(5827..6537)
/gene="Z0405"
/function="orf; Unknown function"
/note="Residues 1 to 188 of 236 are 98.93 pct identical to
residues 1 to 188 of 310 from Escherichia coli K-12 Strain
MG1655: B0316"
/codon_start=1
/transl_table=11
/protein_id="AAG54660.1"
/db_xref="GI:12513133"
/translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICIN
QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
GIDYTEIGAIRWAFAIAPDHPLAFVPEPSPKANCVSTLILWWRTPRIRLIKKWAGCCT
GRSQFWCQISTPNVSARF"
gene complement(6629..6931)
/gene="Z0406"
CDS complement(6629..6931)
/gene="Z0406"
/function="orf; Unknown function"
/note="Residues 1 to 100 of 100 are 98.00 pct identical to
residues 66 to 165 of 165 from Escherichia coli K-12
Strain MG1655: B0317"
/codon_start=1
/transl_table=11
/protein_id="AAG54661.1"
/db_xref="GI:12513134"
/translation="MVWAFFAALAAGWLASVSGLSAFWASVITTVPFSAVVVWQGRFW
LLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATTKRDGY"
gene 7394..7999
/gene="yahD"
/note="Z0407"
CDS 7394..7999
/gene="yahD"
/function="putative regulator; Not classified"
/note="Residues 1 to 201 of 201 are 99.50 pct identical to
residues 1 to 201 of 201 from Escherichia coli K-12 Strain
MG1655: B0318"
/codon_start=1
/transl_table=11
/product="putative transcription factor"
/protein_id="AAG54662.1"
/db_xref="GI:12513135"
/translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNGDLTLLRIILPAKPDLNCVT
RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
gene 8039..8902
/gene="yahE"
/note="Z0408"
CDS 8039..8902
/gene="yahE"
/function="orf; Unknown function"
/note="Residues 1 to 287 of 287 are 97.90 pct identical to
residues 1 to 287 of 287 from Escherichia coli K-12 Strain
MG1655: B0319"
/codon_start=1
/transl_table=11
/product="orf, hypothetical protein"
/protein_id="AAG54663.1"
/db_xref="GI:12513136"
/translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
NFRLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVIDKQNI
ASAVASMMGLGIGLTPSADDYLTGLALILFISGHPAGKYKEEFYLGLQRGRNNTTLLS
AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
LSQTYGGNYVS"
gene 8892..10439
/gene="yahF"
/note="Z0409"
CDS 8892..10439
/gene="yahF"
/function="putative enzyme; Not classified"
/note="Residues 1 to 515 of 515 are 98.64 pct identical to
residues 1 to 515 of 515 from Escherichia coli K-12 Strain
MG1655: B0320"
/codon_start=1
/transl_table=11
/product="putative oxidoreductase subunit"
/protein_id="AAG54664.1"
/db_xref="GI:12513137"
/translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
PVVVCFLGRGETPVDEQGLQFARGTKEAALKAVMLSGVKQEHLDLHTLNQPLITDVRA
RLKPQQKYIRGLFCGGTLCDETMFAVMEKHSDVYSNIQPDPEFRLKDINRSIKHTFLD
FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
ICKGEEA"
gene 10439..11857
/gene="yahG"
/note="Z0410"
CDS 10439..11857
/gene="yahG"
/function="orf; Unknown function"
/note="Residues 1 to 472 of 472 are 99.15 pct identical to
residues 1 to 472 of 472 from Escherichia coli K-12 Strain
MG1655: B0321"
/codon_start=1
/transl_table=11
/product="orf, hypothetical protein"
/protein_id="AAG54665.1"
/db_xref="GI:12513138"
/translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQFDWTPPGQGNM
QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAG
PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDA
MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVAQQREVFEF
VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
QMREITLGENPNVTIPLLGFMGVPSAVDITRVGSSGILPVINTAIAHKDAGVGMIGAG
IVHPPFACFEKAILGWCERYGV"
BASE COUNT 3202 a 2817 c 3278 g 2847 t
ORIGIN
1 atttggatac ctaataagag ttaccacttt taccggctgt atattaaatg tatttctcct
61 gcttttgttt atattttgag ttgatttgag ttcccggata catataatgc gcaggtatta
121 gagactgggg ggaaatgtaa tgataaagtt aagagtgtta acttaaaata agtttttagt
181 agtaacttgc tattttatta ccctctgaac tacatactca gatatgtggt tgccaatgct
241 atgcaaaatt tttgaatttt tatatgcgat gaacagtaac cggaatggca tttaatgcgt
301 tgctgtttat gcaatcttgg ttttatttgg atgtattgct ggagattgtg atgaataaaa
361 tatatcggct aaagtggaac aggtcccgta actgttggag cgtctgctcg gagctgggga
421 gcagagtaaa aggaaaaaag tcccgggctg ttttaattag cgcgataagt ttatattcat
481 ctctggtatt cgccgatgat gtcatcgtaa accaggataa aactattgat tttggcaaag
541 agaaccagag catcgattac cgtattacgg tgacagacaa tgccaatctg gtaatcaatg
601 cgacagatac ttcccgtccg cgtctgactc tcgcttctgg tggtgggttg gatattaccg
661 gaggaaaggt aacaatcaat ggcccactta actttttgct gaaaggtacg gggttcctga
721 atgtctccaa tgctggcagc gagttatatg ctgatgattt gtatgaatca aactcaggca
781 tgagacacga tcgcggctat tttaatgtct ccaacggcgg caaaatccat gttaagggca
841 ccagccgtct gacctatttg cagggaaatg tcagtggtga aggtagccag gtaaattccg
901 aaaccttctt tatgggcgtt tacggcagtt acggtggtaa tcagtacctg tcagttaata
961 acggcggtga agttaatgcc aggaagcaaa ttagcctggg ctattatgat caagtctccg
1021 atacaacact tgctgtttcg gaaggtggta aaatttctgc gcctactatt agtttaagca
1081 ccaactctga gttagcgtta ggggcacagg aaggaagcgc agcgaaggca gcagggatta
1141 ttgatgccga aaaaattgag tttgtgtggg caaagacatc cgagaagaaa atcaccttaa
1201 accacacgga taaagacgcg actatttccg cggatattgt cagtggcagc gagggcctgg
1261 gctatatcaa tgcgctcaat ggcacgactt acttaaccgg tgataactct gcctttagtg
1321 gtaaagtcaa aattgagcaa aatggcgctt tagggatcac ccaaaatata ggtacagcag
1381 agatcaacaa ccgcgggaaa ttacacctga aggctgacga tagcatgacc tttgccaata
1441 agatctctgg caacggtaca ataagtatcg acagtgggac ggtggagttg accggcaata
1501 actatgcatt cagcggatat attgatgttg cttctggtgc tgtcgctgtt atttctgaag
1561 acaagaatat cggtcgtgca gagctggatg tcgatggcaa attgcaaatt aatgccaaca
1621 aagattgggt atttgataac gatcttgaag gtagaggcat tgttgaaata aacatgggga
1681 atcacgaatt ctccttcgat gagtttgctt atacagactg gttccagggt tcactggcgt
1741 tccagaacac gacatttaat ctggaaaaga atgctgagtt tctgcagaaa ggcgggatca
1801 ctgcgggtca gggaagcctg gtaacagtgg gtaagggcgc tcactccatt agcactttgg
1861 gattctccgg cggaaccgtt gattttggtg ccctgacagc aggtgcacag atgacagaag
1921 ggacggtcaa cgttagtaaa acgctggatt tgcgcggcga gggtgtgatt caggtttctg
1981 acagtgacgt tgtccgctca gtatctcgtg atattgactc tgcgttatcg ctcactgaag
2041 tcgatgatgg taacagcacc attaagttgg ttgatgcgca aggtgcggaa gttctgggcg
2101 atgcgggcaa tctgcaattg caggataaaa atgggcaaat cctctccagc agcgcccaac
2161 gtgatattca gcagaatggg caaaaagcgg ccgtcggcac ttacgactat cgtctgacga
2221 gtggggtaaa caatgacggt ctgtatattg gttacggcct gacccagctt gatttacacg
2281 ctaccgacag cgatgctctg gtgctgagct ctaacggtaa aagcgagaat gccgccgatc
2341 tcagcgcaaa gattaccggc agtggtgacc tggcattcag cagccagaag ggtcagaccg
2401 tatcgctttc taacaaagac aacgactata ccggtgttac cgatctgcgc agtgggacgc
2461 ttttgttgaa taacgataac gtgttgggta atacccatga actgcgtctg gcggcagaga
2521 ctgaactgga catgaatggt cacagccaga ccgtgggcac gctcaatggc agcgccgatt
2581 cactgctgag cttaaatggc ggcagtctga cggttaccaa cgggggcact tcaaccggtt
2641 cgttaacggg gagcggagag ctgaatattc agggcggcac gctggacatc gcgggcgata
2701 acagcaacct gacggcgaat gtgaacattg ctaattcggc taatgtcctg gtaagtcatg
2761 cgcagggatt gggtagcgca aacgttgaga acaacggtac cctggcgttg aataatagcg
2821 ctgaaaaaag agcggctgcg tctgtgaatt acgccctggg cggcaatctg accaacaacg
2881 gtacgctgat gaccggaatg tcaggacagc aagctggcaa tgtgttagtg gtgaagggga
2941 actaccacgg taataacggt caactagtaa tgaatacggt actgaatggc gatgactcag
3001 taaccgataa attggttgtc gagggcgata ctagcggcac gactgccgtt acggtgaata
3061 acgctggcgg tacaggtgcg aaaaccctta acggtatcga acttatccat gtagacggta
3121 agtctgaggg cgaatttgtt caggctgggc gtatcgttgc gggggcgtat gactacactc
3181 tcgcgcgtgg acaaggggca aatagtggta actggtatct gaccagcggc agtgattctc
3241 ctgaactgca gccggagcca gacccgatgc cgaatccaga gccaaacccg aatccagagc
3301 cgaaccctaa cccgacacct acgccgggtc cggatctgaa tgtggataat gacctgcgac
3361 cggaggcggg tagctacatt gcgaaccttg cagcagcgaa taccatgttc accacgcgtc
3421 tgcatgagcg tctgggtaat acgtactata ccgacatggt gacgggtgag cagaaacaaa
3481 ccactatgtg gatgcgccat gaaggtggtc ataataaatg gcgtgatggc agcggccagc
3541 tgaaaaccca aagcaatcgc tatgttctgc aactgggagg cgatgtcgcg cagtggagcc
3601 aaaacggcag cgaccgctgg catgttgggg tcatggcggg atatggcaac agcgacagca
3661 aaaccatttc ctcgcgaacc ggttatcgtg caaaagcgag tgtgaacgga tatagcacag
3721 gcctctatgc cacctggtat gccgatgacg agtcgcgtaa tggcgcgtat ctcgacagtt
3781 gggcgcagta cagctggttt gataacacag tgaaagggga tgacttacaa agtgaatcct
3841 ataaatcaaa aggatttacc gcttcactgg aagctggata caaacacaaa ttagctgaat
3901 ttaatggcag ccagggaacg cgtaatgaat ggtatgttca gccgcaagca caggttacct
3961 ggatgggagt caaagccgat aagcaccgcg aaagcaacgg aaccctcgtt catagcaacg
4021 gtgatggcaa tgttcaaacc cgacttggcg taaaaacctg gctgaagagc caccataaaa
4081 tggatgacgg taaatcccgc gagttccagc cgtttgtaga agtgaactgg ctacataaca
4141 gtaaggattt cagcaccagt atggatggcg tgtctgtcac tcaggatgga gcccgaaata
4201 ttgctgagat aaaaaccggg gtggaaggac agctaaatgc caacctgaat gtctggggga
4261 atgtgggcgt tcaggttgcc gataggggat ataatgacac ctctgcaatg gttggcatta
4321 agtggcaatt ctgatctgaa taatgagtaa aaggagagag agccgaacgg gagataattc
4381 ggctctctgt gtcattttct tgcagccagc tttatccgtc agagtgaaga ctcgcagatt
4441 tagctggcgc acaagattta atcaaggtgt gttcaatggc ttcgcatgat ttgagtgttt
4501 ttttggaaga gttcggggca acggtgaatt tgacgttgcc tggtatcgtg tccgaaaaag
4561 aacggctttt actcaagctg ctaatggagg gaatgtcggt tacagaaatc tcacagtaca
4621 gaaatcgcag tgcaaagaca atttcacatc aaaagaagca gctgtatgaa aaactaggca
4681 tccagagtga tattaccttc tggcgggata tcttttttca atatcatccg caagtcatta
4741 gtggcacggg aaataaaaat aatttttata tccctgataa ccgttgtcac catatcgtca
4801 cgcctgaagc catcagtctg gcgttggaaa accatgaatt taaaccgtgg atccaaccgg
4861 ttttctgcgc gcagactggg gtactgacgg gctgtgaagt gcttgtccgc tgggaacatc
4921 cacaaacggg aatcatcccg ccggatcagt ttattcctct ggcggagtca tccggtctta
4981 ttgtcataat gacccgccaa ctgatgaaac agactgcgga tattctgatg ccggtaaaac
5041 atttgctgcc ggataatttc catattggta tcaacgtctc ggcgggttgt tttttggccg
5101 cgggatttga aaaagaatgc ctgaacctgg tcaagaaatt aggaaacgat aaaatcaaac
5161 tggttctcga gctaacggaa cgtaacccta ttccggtaac gccagaagcc agagcgatat
5221 ttgacagcct tcatcagcat aacattacct ttgcgctgga tgactttggt acgggttatg
5281 cgacctatcg ttatctgcag gcgtttccgg tcgattttat taagatcgat aagtcatttg
5341 tgcaaatggc gggtgtcgac gaaatatccg gtcatattgt ggacaatatt gtcgaactgg
5401 cgcgtaagcc tggtctgagt atcgtggcgg aaggggtaga aacccaggag caggcggatt
5461 taatgatcgg taaaggcgtt cactttttgc agggctattt gtactctccg ccagtaccgg
5521 gtaataaatt tatctctgaa tgggtaatga aagcaggtgg ttgatgtaaa ccgctattca
5581 cagcgcatcg ggaggttggc agcgattaat tctcccgatg cagtaaatcc tgatagatcc
5641 ccgttaatat gccatttggc gcaaattgtt ttttaatcca ctgcgtcacc tgacccgtag
5701 cagaatgctg agtcgccagt aacatgcgtg aatcctggcg cgggttatgg atttgtcggg
5761 taaccagcag ggattgcgcc atcgcctcac ggaccatgta atctggcaaa aaaacaatcc
5821 cttcacctaa aatctggcac tgacatttgg tgttgaaatc tggcaccaga attgactcct
5881 gcccgtgcag caaccagccc acttttttat taatcgtatg cgcggtgtcc tccaccataa
5941 tattagggta gagacgcagt tggctttcgg cgatggttcc ggcacaaagg ctaacgggtg
6001 atccggggcg atagcaaaag cccagcgaat cgcgccaatt tcagtgtaat caataccgcc
6061 gccgtccagc agcgtgtcgg gtgcgccgat agcgatattt gcctgattat taataatcgc
6121 atcccagacg ccgttataca cttcggtggt gacggtaatc tggcaggtag gaaactgctt
6181 tttcagcacc tgtaataagc gtgcggtgtg tttgggcgta taaagcaact gattaataca
6241 aatgcgcaca cgcgcttcta tgccctgcga aatagtatcg atgctgcgtt tgatggcgtg
6301 aaaatcattc agcaggtcgg tagctttgcg gaaaaaataa cgcccggact ccgttaactc
6361 aatgctgcgg gtactgcgag tgaacagcac cacatccagc cctgtttcca ttcgcttgat
6421 ggtgtagcta atggcggaag tggttaaacc caactcttct gcggctttac tgaaactgcc
6481 aaaacgcgca gcggtagtaa atgccaacag attctcttcg gtaaaaattg agttcattaa
6541 accattcccg ccattatcta atatgaattt ctccaagcat aactgtagag gtatcaatta
6601 gagatgggta atcatttttg aataactttt aatacccgtc gcgtttagtc gtcgcttcgc
6661 ttaatttttg tccgccatat tctgaaatta tccccacgca gttacccgcc agaaaaccca
6721 gtaacgtcac cgtccagttc atcccgctgg caaaaaacag cgtcatgccg agaaagccac
6781 cgggaataaa tgacagtaac cagaaacgcc cttgccagac caccaccgcc gagaagggta
6841 cggtagtaat tacgctcgcc cagaacgcgg acagtccact tacagaggcc agccaaccgg
6901 cagccagcgc ggcgaaaaac gcccacacca tcccggaata attaaccgac agacttctga
6961 taaaccccga tttaccgccg cctgcggcat aaaaactgca aaaggcgacg aagccaatgg
7021 ttcctaataa ttcctaataa ttcccatccc tgagagagcc cgacatgtga agacactaac
7081 tgccaaagcc ctgcacaaat accgacggtg acacccgttg ccgtgagtcc gttcatcttg
7141 ttcccctctg gttagacatg gacgaaagct actcttacat gtgcagacta tagagaaata
7201 aaacctgatt gagtgaaagg gtatcgggtc aaagaaacaa atattgcact accgcacact
7261 gcgaaaagat tgttgaacat cattcaacaa aaaggcgaaa tacggcgaat taaatttaag
7321 cgggttcttt tatcagatta tcgttgctat tctcaattca tcgaaaacag ccacaaaaac
7381 caggggaatg tgaatgagta taaaaaatct acctgccgac tatttattgg ctgcacaaca
7441 gggtgatatc gataaagtaa aaacctgcct tgcgctgggt gtcgatatta atacctgcga
7501 tcgtcagggg aaaacggcaa ttacgctggc aagtttatat cagcaatatg cttgcgttca
7561 ggcattaatt gatgccggag cggatattaa taagcaagat catacctgtt taaatccttt
7621 tttaattagc tgtctgaacg gtgatttaac gctgctacga attattttac cggctaaacc
7681 agaccttaat tgcgtcaccc gttttggcgg tgtcggcctg acgcctgcct gtgaaaaagg
7741 ccatttaagt attgtaaaag agcttttggc gcatacggaa attaacgtta accagaccaa
7801 ccatgttggc tggacgccac tactggaagc gattgtgctt aacgatggcg ggattaaaca
7861 gcaggcgatt gtgcagttat tgctggaaca cggtgccagc ccgcatctga ccgataaata
7921 tggcaaaacg ccactggaac tggcgcggga acggggcttt gaagagattg cgcagttact
7981 gattgccgca ggtgcataaa ccgggaggct tgctatcaac acaccagaaa aacggtgtgt
8041 gtgggcgcta actgcggatg cggattttct ggcgcagcga gggcaaggac aggttgaaca
8101 ggtctttgcc agagcggtaa atatcgcact cccggctcgc cagcagttgc tgacgctgct
8161 ttgtgaagag tacgacaatg cgccaaacag ttgtcggttg gcactcactc actttgatga
8221 tctgttccgg catggtgata aggttcagtt tgacgatcaa ggtattacgg ttggtcaaca
8281 tcttcatata gagatgagtc gttgtcggcg ttggctgtcc ccaaccttgc aaatgaccgc
8341 tgtgaatttt cgccttatcg cctggcaaca gtggcacgac atcattcatc agcacctggg
8401 ggaaaatgaa accctgttta attatcgcgg cgataatccg ttttatcagg cgttaaataa
8461 agaattacat attaaacgac gggcagttat acaggcagta atcgataaac aaaatatcgc
8521 ctcagcggtc gccagtatga tgggcttagg gattggcctt acgccatcag ccgatgatta
8581 tttaacaggt ctggcactta ttttatttat ttccgggcat ccggcgggaa aatacaaaga
8641 ggaattttat ctcggcttgc aacgcggcag aaataatacc acgttattaa gtgccataac
8701 gctggaagcc gcattacaac aacgctgccg ggaaaatatt catcgtttta ttcacaacat
8761 tatttatgac atccctggga acgcaactca ggcaatagaa aaaattaaac atattggctc
8821 cagttccggc tgcgacatgc tgtatggcat ggccgatggt tgtgcgctga gccaaaccta
8881 cggagggaat tatgtcagtt aaaatagtca ttaaaccgaa tacctatttt gattctgtct
8941 cgctgatgtc tatctccacg cgtgcaaata aactcgacgg cgtcgagcag gcatttgtgg
9001 cgatggcgac cgaaatgaac aaaggtgtgc tgaaaaattt aggactgctg acgccggagc
9061 tggagcaggc gaaaaacggc gacctgatga ttgtcatcaa tggtaaatcg ggggcggaca
9121 acgagcagtt gctggtggag attgaagaac tgttcaacac caaagcgcaa agcggctcgc
9181 acgaggcgcg ttacgccact attgccagcg ccaaaaagca tatcccggaa agtaacctgg
9241 cggtgatttc ggtcaacggt ctgtttgccg ctcgcgaagc gcgtcaggcg ctgcaaaacg
9301 atctcaacgt gatgctgttt tccgataacg tctcagttga agatgaactg gcgctcaagc
9361 aactggccca cgaaaaaggg ctgctgatga tggggccaga ctgcggcacg gcgattatca
9421 acggtgcggc gctctgcttt ggtaacgccg tgcgtcgcgg caacatcggt attgttggcg
9481 catccggcac cggcagtcag gagttgagcg tccgcattca tgaatttggc ggcggcgttt
9541 cgcaactgat tggcaccggc gggcgcgacc tgagcgagaa aatcggcggc ctgatgatgc
9601 tcgacgccat cgggatgctg gaaaacgatc cgcaaactga aatcattgcg cttatctcca
9661 aaccgcctgc gcctgcggtg gcccgcaaag tgctggaacg tgcgcgcgcc tgccgcaagc
9721 cggtggtcgt ttgcttcctc ggtcgtggcg aaacgccagt ggatgagcag gggctacagt
9781 ttgcccgcgg caccaaagag gcagcgctaa aagcggtgat gctctccggc gtgaaacaag
9841 aacatctcga cctgcatacc ctgaaccagc cgttgattac tgacgtgcgc gctcgcctga
9901 agccgcagca gaaatacatt cgtggcctgt tctgcggtgg cacgctgtgc gatgaaacga
9961 tgttcgcggt gatggaaaaa cacagcgatg tctacagcaa catccagccc gatccggaat
10021 tccgcctgaa ggatatcaac cgcagcatca aacacacctt cctcgacttt ggcgatgacg
10081 acttcaccaa cggcaagccg cacccgatga ttgaccctac caaccgcatc agccgcttga
10141 tcgaagaggc gcgcgatcca gaagtggcgg tgatcgtgat ggattttgtg ctcggatttg
10201 gatcgcatga agatccggtc ggttccacca tcgaggcgat caaagaagcg aaagcgatcg
10261 ccgctgccga aggacgcgag ttgatcattc tcgcctatgt gctgggtacc gatcttgata
10321 cgccatcgtt agaacaacaa agccagatgc tgcttgatgc cggcgtgatt ctggcgagca
10381 gcagcaccaa taccggattg ctggcgcgtg aatttatctg caaaggggag gaagcctgat
10441 gagccagtca ctgtttagcc aaccattgaa cgttattaac gtcggcatcg ccatgtttag
10501 cgatgacctg aaaaagcagc atgtagaagt gactcaattc gactggacgc cgccggggca
10561 gggcaatatg caggtggtgc aggcgctgga taacattgcc gattcgccgc tggcagacaa
10621 aatcgccgcc gctaaccagc aggcgctgga gcgcattatc cagtcgcatc cggtgctgat
10681 tggttttgat caggcgatta acgtggtgcc gggcatgacg ccgaaaacca ttcttcacgc
10741 cgggccgccg atcacctggg aaaaaatgtg cggcgcgatg aaaggcgcgg tcaccggagc
10801 gctggtgttc gaaggactgg cgaaagatct cgacgaggcg gctgaactgg cggcttccgg
10861 ggagatcacc ttctcgccgt gtcacgagca cgactgcgtg ggatcgatgg cgggtgtgac
10921 ctcggcctcg atgtttatgc acatcgtaaa aaacaaaacc tacggcaaca tcgcttatac
10981 caacatgagc gagcagatgg cgaagatttt gcgtatgggc gctaacgacc agagcgtgat
11041 tgaccgcctg aactggatgc gtgatgtgca gggaccaata ctgcgcgacg cgatgaaaat
11101 tatcggcgaa atcgatctgc gcttaatgct ggcgcaggcg ctgcatatgg gcgatgagtg
11161 ccataaccgc aataacgccg ggacgacgct gctgattcag gcgctgacgc cggggattat
11221 ccaggcgggc tattccgtcg cgcaacagcg cgaagtgttt gagtttgttg ccagtagcga
11281 ttacttctcc ggcccgacgt ggatggcgat gtgtaaagcg gcgatggatg cggcgcacgg
11341 catcgaatac agcaccgtcg ttaccaccat ggcgcgtaac ggcgtcgagt tcggcctgcg
11401 ggtgagcggc ctgccggggc agtggtttac cggcccagcg cagcaggtca tcggcccgat
11461 gtttgctggt tataagccgg aagattcggg gctggatatc ggcgacagcg ccatcacaga
11521 aacctacggt attggcgggt ttgccatggc gaccgcgcct gcaatcgtcg cgctggtggg
11581 gggcacggtg gaagaggcta tcgatttctc ccgtcagatg cgcgaaatca cccttggcga
11641 aaaccccaac gtcaccattc cgctgctcgg ttttatgggc gtgccgtcgg cagtcgacat
11701 cacccgcgtg ggtagcagcg gcattctgcc ggtgatcaac accgccatcg cccataaaga
11761 tgcgggcgtc ggcatgattg gcgcgggcat tgtgcatcca ccattcgcct gcttcgagaa
11821 agccattctt ggctggtgcg aacgttacgg cgtttgacct acctgttcat accggatgcg
11881 gcgtgaacgc cttatccggc ctacgaatgg cgcaagaatc tgtaggcctg ataagcgtag
11941 cgcatcaggc atttgtcacc attgccggat gcggcgtgaa cgccttatcc ggcctacaag
12001 tggcgcaaga atttgtaggc ctgataagcg tagcgcatca ggcatttatc accattgccg
12061 gatgcggcgt gaacgcctta tccggcctac gaatggcgca agaatctgta ggcctgataa
12121 gcgtagcgca tcaggcattt gtca
//
